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For over 30 years, Best Friends Animal Society has been running the nation’s largest no-kill sanctuary for companion animals and building effective programs that reduce the number of animals entering shelters. The mission of Best Friends Animal Society is to bring about a time when there are No More Homeless Pets. The organization does this by helping end the killing in America's animal shelters through building community programs and partnerships all across the United States.

Founded in 1947, Dana-Farber Cancer Institute is committed to providing expert, compassionate care to children and adults with cancer, while advancing the understanding, treatment, cure, and prevention of cancer and related diseases. As an affiliate of Harvard Medical School and a Comprehensive Cancer Center designated by the National Cancer Institute, the Institute also provides training for new generations of physicians and scientists, designs programs that promote public health particularly among high-risk and underserved populations and disseminates innovative patient therapies and scientific discoveries in Boston, across the United States and throughout the world.

The mission of the University of Michigan is to serve the people of Michigan and the world through preeminence in creating, communicating, preserving and applying knowledge, art, and academic values, and in developing leaders and citizens who will challenge the present and enrich the future.

The Stephen Siller Tunnel to Towers Foundation is to honor the sacrifice of firefighter Stephen Siller who laid down his life to save others on September 11, 2001. We also honor our military and first responders who continue to make the supreme sacrifice of life and limb for our country.

Nancy G. Brinker promised her sister that she would do everything in her power to end breast cancer forever. That promise is now Susan G. Komen for the Cure®, the global leader of the breast cancer movement, having invested more than $2.2 billion since inception in 1982. As the world’s largest grassroots network of breast cancer survivors and activists, we’re working together to save lives, empower people, ensure quality care for all and energize science to find the cures. Thanks to events like the Susan G. Komen Race for the Cure® and the Susan G. Komen 3-Day for the Cure®, and generous contributions from our partners, sponsors and fellow supporters, we have become the largest source of nonprofit funds dedicated to the fight against breast cancer in the world.

The Tigray Development Association is a member-based 501(c)(3) nonprofit organization established in August 1989 in Washington DC. Our primary objective is to contribute to the improvement of the livelihood of the people of Tigray through human resource development and the enhancement of health services. We address the core causes of the problems by fostering self-sufficiency at the community level, empowering Tigrayans as change agents, and developing successful collaborations with local and international communities and partners.

Chartered in 1934, the Animal Defense League of Texas (ADL) is the oldest no-kill shelter for abandoned, abused, or neglected dogs and cats in South Central Texas. Through the operation of two facilities, a centrally located 12-acre campus and the city-owned Paul Jolly Center for Adoptions, ADL saves the lives of vulnerable animals primarily originating from the most poverty-stricken communities in San Antonio. A full veterinary hospital housed on the main campus provides spay/neuter surgeries, vaccinations, and microchipping for all pets in ADL’s care. In addition, ADL performs specialized surgeries for animals with complex medical conditions and is the first organization to provide no-cost mobile wellness clinics to historically underserved areas. ADL’s partnership with Animal Care Services (ACS) is instrumental in helping the City of San Antonio back to achieving a “No-Kill” status.

California Community Foundation's mission is to lead positive systemic change that strengthens Los Angeles communities. We envision a future where all Angelenos have the opportunity to contribute to the productivity, health and well-being of our region. We believe our common fate will be determined by how successfully we improve the quality of life for all residents. The impact we help create is of, by and for Los Angeles, because the community is our foundation. CCF is driven to find long-term, systemic solutions addressing the root causes of the most pressing issues facing Los Angeles County. Since 2000, more than $200 million has been given in discretionary grants, impacting hundreds of thousands of lives and helping to transform entire communities. Every one of those grants represented the legacy of a donor who was dedicated to creating a healthier, more prosperous and empowered L.A.

For over 150 years, the ASPCA has worked tirelessly to put an end to animal abuse and neglect. We are a national leader in the areas of rescue, adoption and welfare, and your tax-deductible donation will help fight cruelty and make a life-changing difference for animals across America. Thank you for making the ASPCA and the animals we serve a part of your life.

Our mission is to be a relentless force in building a world of strong, healthier lives, free of cardiovascular diseases and stroke. Our mission drives everything we do. We’re the nation’s leader in CPR education training. We help people understand the importance of healthy lifestyle choices. We provide science-based treatment guidelines to healthcare professionals to help ensure the best treatment for every patient, every time. We educate lawmakers, policy makers and the public as we advocate for changes to protect and improve the health of our communities.

The Michael J. Fox Foundation is dedicated to finding a cure for Parkinson's disease through an aggressively funded research agenda and to ensuring the development of improved therapies for those living with Parkinson's today. The Foundation's focus is increasingly on clinical and translational research, crucial to making strides toward a cure and improved therapies for those living with Parkinson's today.

To eliminate Alzheimer's disease through the advancement of research; to provide and enhance care and support for all affected; and to reduce the risk of dementia through the promotion of brain health. The Alzheimer's Association is the world's leading voluntary health organization in Alzheimer's care, support and research. We value inclusivity, community, accountability, agility, and integrity. Our commitment to transparency, research, and diversity and inclusion helps to fulfill our vision: a world without Alzheimer's and all other dementia. In 2021, the Alzheimer's Association invested over $70 million in research, launched two new campaigns "Any Given Moment" and "More Time", and strengthened partnerships with faith-based communities. The Alzheimer's Association's powerful advocacy witnessed the Improving HOPE for Alzheimer's Act signed into law through the Association's leadership. At the beginning of the COVID-19 Pandemic, the Association's Walk to End Alzheimer's participants walked in small groups in their neighborhoods to raise $86 million.