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RAINN (Rape, Abuse & Incest National Network) is the nation's largest anti-sexual violence organization and was named one of "America's 100 Best Charities" by Worth magazine. RAINN created and operates the National Sexual Assault Hotline (800.656.HOPE and online.rainn.org) in partnership with more than 1,100 local rape crisis centers across the country and operates the DoD Safe Helpline for the Department of Defense. RAINN also carries out programs to prevent sexual violence, help victims and ensure that rapists are brought to justice.

Seeking to put God’s love into action, Habitat for Humanity brings people together to build homes, communities and hope.

JDRF's mission is to find a cure for type 1 diabetes and its complications through the support of research. It is also committed to developing new and better treatments that improve the lives of people with type 1 diabetes in the near term and keep them healthy while we advance toward a cure. JDRF’s promise is to progressively remove the impact of T1D from the lives of those living with the disease until it is no longer a threat to them or their families. Formerly known as JDRF International or Juvenile Diabetes Research Foundation

The mission of the American Diabetes Association (the Association) is to prevent and cure diabetes and to improve the lives of all people affected by diabetes. Diabetes is a disease in which the body does not produce or properly use insulin.  Insulin is a hormone that is needed to convert sugar, starches and other food into energy needed for daily life.  The cause of diabetes continues to elude the medical community, although research has shown that both genetics and environmental factors such as obesity and lack of exercise appear to play roles.

Autism Speaks is dedicated to promoting solutions, across the spectrum and throughout the life span, for the needs of individuals with autism and their families. We do this through advocacy and support; increasing understanding and acceptance of people with autism; and advancing research into causes and better interventions for autism spectrum disorder and related conditions. ​Through partnerships and collaboration, we are committed to: ​​Increasing global understanding & acceptance of people with autism Being a catalyst for life-enhancing research breakthroughs Increasing early childhood screening & timely interventions Improving the transition to adulthood Ensuring access to reliable information & services throughout the life span.

The mission of Zebra Coalition is to empower LGBTQ+ youth to thrive.

To improve the quality of life for all LGBTQ+ people in Upstate, South Carolina.

The Knights and Orchids Society (TKO) envisions a future where Transgender, Lesbian, Bisexual, and Gay (TLBG) Black people are empowered to live full and healthy lives free from harm. Our mission is to build the power of TQBLG Black people across the south by providing a spectrum of health and wellness services designed to address the social determinants of health that negatively impact our communities. Since 2019, we have provided 258 clients with services through our primary program Fast, Affirming, Innovative Testing and Healthcare or FAITH.

Crohn's disease and ulcerative colitis are collectively known as inflammatory bowel disease (IBD) because they cause severe inflammation of the intestinal tract, and have common symptoms. The cause remains unknown, and there is no medical cure. The Crohn's & Colitis Foundation of America was founded in 1967. Its mission is to find a cure for Crohn's disease and ulcerative colitis and to improve the quality of life of children and adults affected by these diseases.

Samaritan's Purse is a nondenominational evangelical Christian organization providing spiritual and physical aid to hurting people around the world. Since 1970, Samaritan's Purse has helped meet needs of people who are victims of war, poverty, natural disasters, disease, and famine with the purpose of sharing Gods love through His son, Jesus Christ. The organization serves the church worldwide to promote the Gospel of the Lord Jesus Christ.

The Pancreatic Cancer Action Network (PanCAN) is a nationwide network of people dedicated to working together to advance research, support patients and create hope for those affected by pancreatic cancer. Our mission is to take bold action to improve the lives of everyone impacted by pancreatic cancer by advancing scientific research, building community, sharing knowledge, and advocating for patients. PanCAN has invested more than $149 million in research since 2003. In the past year our nationwide PurpleStride community raised $11.8 million to fund our critical research and programs and services for patients. We have more than 700 PanCAN volunteer leaders driving local community action in our nationwide moment.

The National Multiple Sclerosis Society's mission is to cure multiple sclerosis while empowering people affected by multiple sclerosis (MS) to live their best lives. The organization pledges to accelerate cures through global leadership, and improve access to personalized, affordable, high-quality MS healthcare. It empowers people affected by MS to solve everyday challenges and strengthens the MS movement through more and deeper connections.