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Talbot Humane has been helping animals in Talbot County, Maryland, since 1932. For over 80 years our goals have been: To rescue animals from neglect; To place companion animals into loving homes; To reunite lost pets with their owners; and To reduce pet overpopulation through aggressive spay and neuter programs.

Street Tails Animal Rescue is a Philadelphia-based 501(c)(3) nonprofit that rescues overlooked and vulnerable dogs, provides medical care, rehabilitation and individualized attention in a kennel-based facility, and works to place each dog into a safe, well‑matched permanent home. The organization is privately funded and focuses on personalized, careful adoption matches.

Street Cat Clinic is a 501(c)(3) veterinary surgical clinic focused on high-volume spay/neuter (TNR) and basic veterinary care for outdoor/community cats in southeast Florida. They work with trappers and rescue partners to provide no‑cost sterilization, vaccinations, and select surgical care for community cats and kittens being prepared for adoption.

Skydog Ranch & Sanctuary rescues at-risk wild mustangs and burros (and other equines) from auctions, kill pens, and unsafe situations, then provides lifelong care, rehabilitation, and—where possible—reunites family bands. The organization operates an 11-acre ranch in Malibu and a large open sanctuary in Oregon and emphasizes both animal welfare and public education/advocacy about the plight of wild horses and burros.

Serenity Place Animal Rescue is a small Polk County 501(c)(3) rescue that works to save, care for, and rehome homeless and abandoned dogs and cats—frequently pulling animals from high‑kill animal control centers—and operates primarily through volunteers and a network of foster homes.

Saving Pets At Risk (SPAR) is an all‑volunteer animal rescue that rescues, vets, rehabilitates, and places abandoned or injured dogs (and formerly cats) from the Shawnee area; it relies on donations and fosters to provide medical care and to find permanent homes while also promoting spay/neuter and community education to reduce pet overpopulation.

Rocky Mountain Lab Rescue is a volunteer-run 501(c)(3) that rescues, vets, transports, and rehomes Labrador Retrievers and Lab mixes—prioritizing dogs at risk in overcrowded or high‑kill shelters. They operate via donations and foster homes to provide medical care, transport, and placement into permanent homes.

The organization works to reduce animal suffering on the island of Vieques by operating a temporary shelter and adoption program, providing spay/neuter services, and running a low-cost veterinary clinic so low-income owners and community animals can receive care.

Wellington Humane Society is a no‑kill 501(c)(3) serving Sumner County that rescues, cares for, and places homeless dogs and cats into responsible homes. The organization also offers community programs (low‑cost spay/neuter, microchipping, vaccination clinics and education) and relies primarily on donations and volunteers to reduce pet overpopulation and support animal welfare.

Two by Two Rescue is a no-kill animal rescue that saves, vets, fosters, and rehomes abandoned, abused, and stray animals without regard to age or medical condition, and works to keep pets in their homes by providing relief and education to people in crisis.

Cherryland Humane Society is a no-kill animal shelter in Traverse City that provides temporary care, medical attention, and behavioral support for dogs and cats while working to place them in responsible, loving permanent homes; it also promotes animal welfare and community education.

THE MISSION IS TO END THE SUFFERING OF ANIMALS DUE TO ABUSE, OVERPOPULATION, AND OTHER FACTORS. TO HELP FAMILIES WHO ARE ECONOMICALLY DISPLACED BY OFFERING AN ECONOMICAL SANCTUARY FOR THEIR PETS THEY CAN NO LONGER KEEP AND PROVIDE THE PUBLIC WITH HELP BY OFFERING LOW COST OR NO COST SERVICES FOR ANIMALS SUCH AS PERFORMING SURGERIES, REHABILITATIONS AND TREATMENTS.